(Senior) Scientist - Trace Organic Impurities

Jobinhalt

Based on your professional experience and educational background, we have the flexibility to tailor the position’s level and responsibilities accordingly.

Job Description

Within Janssen R&D, a member of Johnson & Johnson’s Family of Companies, we are recruiting a (Senior) Scientist for trace level quantification of organic impurities, with a specific focus on nitrosamines.

Janssen R&D develops treatments that improve the health and lifestyles of people worldwide. Our development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, pulmonary hypertension and reproductive medicine. The successful candidate will be employed in our Analytical Development (AD) organization, responsible for Global Therapeutics Development and Supply (TDS) Organization.

The (Senior) Scientist will join the Advanced Material Characterization and Investigations (AMCI) group within AD. AMCI is an international and diverse multidisciplinary team of scientists leading advanced characterization and mechanistical understanding of our drug substances and drug products. We are also leading analytical investigations for commercial and R&D portfolio.

Within AMCI, the Advanced Molecular Analysis (AMA) team is a group of analytical centers of excellence in structure elucidation (by high-resolution Mass Spectrometry and NMR), organic trace analysis, excipient & polymer characterization, and oligonucleotide & peptide analytics.

We are currently seeking a skilled and enthusiastic Analytical Chemist to join our AMA team and contribute to our ongoing efforts in quantifying trace-level organic impurities in various matrices and pharmaceutical products. For this laboratory-based position, you will lead the development and implementation of analytical test methods for nitrosamines, for which your analytical and mass spectrometry background will be required. You will also work together with internal specialists on root cause investigations and search for innovative approaches for optimal analyses. The position is based in Antwerp, Belgium.

Key Responsibilities

• Design, develop, validate and transfer analytical methods for the quantification of trace-level organic impurities, specifically nitrosamines, in various matrices and in accordance with regulatory guidelines and company standards.
• Lead root cause investigations related with trace-level organic impurities for R&D portfolio, from early to late development phase, thereby contributing to process improvement initiatives and enhancing product quality.
• Apply state-of-the art scientific knowledge to ensure high-quality of the delivered results.
• Collaborate closely with cross-functional teams and show ability to learn and explore new techniques.
• Initiate and lead collaboration with e.g. universities to expand our external innovation network.
• A PhD degree in analytical chemistry or related field; or a Bachelor’s degree in a related science with a minimum of 12 years of experience.
• Expertise in developing analytical test methods for the quantification of trace-level organic impurities, particularly nitrosamines, in pharmaceutical products is required.
• Proficiency in utilizing analytical techniques such as LC-MS, GC-MS, or other relevant techniques for impurity analysis.
• Knowledge of regulatory guidelines (e.g., ICH, EMA, FDA) related to analytical validation is an advantage.
• Strong attention to detail and ability to work independently with minimal supervision.
• Strong track record of scientific contributions including peer reviewed publications, or patents, or presentations at international meetings is considered a plus.
• Excellent English scientific communication skills, both written and spoken.
  
  

Our offer

An exciting position in an international and dynamic environment with continuous learning and growth opportunities! An attractive remuneration package with additional benefit packages (for example hospital insurance, and other health care incentives if applicable). An inclusive team environment where diversity and different opinions are respected and valued, and the importance of a good work-life balance is recognized.

Diversity, Equity and Inclusions

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.