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Preclinical Development Leader
Ver: 120
Día de actualización: 07-11-2025
Categoría: IT - Software
Industria: Staffing Recruiting
Posición: Mid-Senior level
Tipo de empleo: Full-time
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Contenido de trabajo
LocationCharleroi, BelgiumBusiness SectorBiotechnologyContact emailJob ref22402Published12 days agoTitle: Preclinical Development Leader
Location: Charleroi, Belgium
We are in search of a seasoned and visionary leader to direct and oversee preclinical research and nonclinical development activities for our client burgeoning portfolio of neurovascular-focused therapies. The ideal candidate will possess an in-depth understanding of drug discovery and development principles and a proven track record of success in leading preclinical teams.
Responsibilities
- Steer and lead all facets of preclinical development, encompassing a diverse range of product modalities (small molecules, antibodies, proteins, and viral or non-viral gene delivery systems)
- Construct and manage a team of highly skilled preclinical scientists with a wide array of expertise
- Formulate comprehensive and well-structured plans and budgets for the preclinical team
- Contribute to crafting target product profiles and preclinical development strategies to advance assets from discovery through candidate selection and IND-enabling studies
- Design, plan, and oversee in vivo pharmacology, safety, and toxicology studies
- Nurture strong collaboration with internal and external research teams, ensuring alignment and maximizing the impact of the preclinical group
- Establish and maintain collaborative partnerships with academic institutions and CROs
- Oversee the development and documentation of study protocols, data review, analysis, and interpretation, ensuring timely reporting of outcomes
- Provide insights and contribute to go/no-go decision-making, including the identification and selection of potential preclinical candidates
- Proactively participate in issue-resolution teams, offering valuable contributions to hypothesis generation
- A PhD in Pharmacology, Toxicology, or a related discipline, complemented by postdoctoral or equivalent experience
- Over 10 years of proven industry experience in nonclinical assessment of novel therapeutics, preferably for a variety of product modalities targeting CNS disorders
- A comprehensive grasp of drug discovery and development principles, coupled with a firm understanding of regulatory requirements
- A demonstrable track record of leading nonclinical drug development programs (pharmacology, toxicology, formulation, regulatory, and DMPK) for small/large molecules and/or advanced therapy medicinal products
- Expertise in designing and executing a wide range of animal model studies, particularly in the context of CNS disorders
- Proven experience in managing and leading teams in a biotech environment
- Exceptional interpersonal skills that foster a positive and collaborative work environment, coupled with diplomatic and critical thinking abilities
- Highly effective communication skills, with a demonstrated ability to communicate complex scientific concepts in both written and verbal forms
- Strong analytical and problem-solving skills, with the ability to think critically and identify innovative solutions
- Collaborate closely with the company’s founders and a team of world-renowned scientists
- Embark on a challenging and rewarding endeavour to advance innovative therapies for patients in need
- Become a part of a highly motivated, international, and passionate team
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Plazo: 22-12-2025
Haga clic para postularse como candidato gratuito
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