Senior Associate Scientist

le contenu du travail

Small Molecule Method Development is a department within Discovery and Manufacturing Sciences (DPDS) / Chemical and Pharmaceutical Development and Supply (CPDS). The department is responsible for Small Molecule Method Development, Method Validation, Method Transfer and support. This includes Active Pharmaceutical Ingredients, Drug Products, Chemical Raw Materials, Starting Materials, Intermediates and In-Process Controls from early development through the lifecycle for commercial products. We also provide analytical support for all regulatory filings (CTA/IND, NDA/MAA, Post Approval Submissions), Inspections and investigations. As well as focused analytical base business support for the Small Molecule (SM) R&D and Manufacturing product portfolio. Finally we provide development and implementation of Process Analytical Technology (PAT) / New Innovative Analytical Technology Platforms for Small Molecules and Cleaning Validation. In the SMMD department in Beerse, Belgium, we are currently looking for a (m/f) Senior Associate Scientist – Liquid chromatography and mass spectrometry expert (LC-MS UHPLC) Job description You are responsible for the planning, coordination and execution of the analytical experimental work (method development, validation, transfer) the main part of this experimental work focusing on analytical methods for assay/purity, content uniformity, ID, moisture and solvents You independently lead multiple assigned projects: establishes priorities, checkpoints, and time frames in line with the project- and team objectives/deliverables You will collaborate closely with colleagues from analytical, API and Drug product development You advise and inform management and stakeholders of technical requirements, about potential scientific challenges and risks, prioritization or resources conflicts and makes suggestions to resolve or mitigate these You initiate ideas to improve the support and efficiency of the analytical method development/validation/transfer activities for the R&D portfolio You ensure that applicable guidelines, established operating procedures and safety regulations adhering to company work standards are being followed You author and review technical reports, protocols and standard operating procedures You maintain knowledge of Good Manufacturing Practices (GMP) and ICH Guidelines Qualifications You hold an advanced Mast of Science degree (MSc.) in Analytical Chemistry, Pharmaceutical Technology or related science with at least 3 years of relevant experience In-depth technical knowledge and experience for developing/validating and transferring analytical methods in support of the R&D project portfolio with major focus on techniques as Liquid Chromatography (UHPLC), Mass Spectrometry (Single Quad) is required. Knowledge and/or experience with oligonucleotide/oligopeptide Analytical method development is preferred. You can work independently, though you are also an excellent collaborator and like to work in a multidisciplinary, inter departmental and cultural divers’ context You can oversee projects in a professional way with respect to deadlines and with a good sense of urgency You ensure high scientific quality standards for experiments and take on responsibility for these experiments You are a prudent risk-taker, who thinks of innovative and creative solutions What is in it for you? • Contributing to our mission to continue to bring transformational new medicines to patients for a world without disease. • Being part of a motivated and experienced research team in an innovative working environment • Through mentoring programs, e-university and on the job training, we ensure your personal development in a global company • A competitive salary, on-site sport accommodations, no fixed holiday planning with 39 holidays, health/energy programs and other benefits for you and your family Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law. Primary Location Belgium-Antwerp-Beerse- Organization Janssen Pharmaceutica N.V. (7555) Job Function General Administration Requisition ID 2206023307W