Vice President, Manufacturing Science And Technology (MSAT)

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Site Name: Belgium-Wavre

Posted Date: Oct 13 2021

About The Role

The Vice President, Head of Manufacturing Science & technology (MSAT) owns the technical ecosystem within GSK Vaccines Manufacturing and connects the business needs with the technical functions. Reporting to the Senior Vice President of GIO, (s)he sits on the Industrial Operations Leadership Team (IOLT) and is responsible for leading the global MSAT function of ~230 FTE to meet the business objectives of GSK Vaccines, defining and directing the strategy to ensure continuous supply of vaccines to agreed customer requirements, quality standards and financial targets. The team is approximately 70% located in Wavre and 30% shared across Rosia (Italy), Marburg (Germany) and Dresden (Germany). The role incorporates the significant scale and complexity of one of the largest vaccine portfolios in the industry as well as a wide variety of established technical platforms and new technologies.

The Work Of The MSAT Function Includes

• Product & Technical Life-Cycle Management Teams whose main role is to coordinate and manage the life-cycle of all licensed products (change control, critical master data management, Regulatory interface, Product & Process evolution in the short-and-mid-term, and troubleshooting major issues in manufacturing areas).
• Global Validation standards and tools (including both Product and Process Validation).
• A center of competencies to drive improvements and innovation of key vaccine manufacturing technologies.
• All product and technical transfers across manufacturing operations from product launch onwards (e.g. site to site, new product introduction to site, and site to external).
• Ownership of global business processes.
• Process Science laboratories with capabilities to characterize and improve processes using small scale models.
• Project Management.
  

The VP, Head of MSAT leads by influence, using a very high level of technical & scientific knowledge related to Biomanufacturing processes. Strong relationships must be built and maintained with R&D, Quality, Engineering, Production, Product Strategy, both within GSK and externally.

The VP, Head of MSAT should be able to work effectively with diverse people and groups globally, simplifying complexity to help colleagues understand, support and apply the technical changes and innovations that the GSK Vaccines unit of the new GSK will need to be sustainable.

This role has broad impact across all production and development related processes. Strong influence will need to be built and maintained with R&D and Quality to ensure that quality-by-design principles are incorporated from an early stage prior to the industrialization steps for new vaccines. These same principles will be applicable for the changes requested to support regulatory, commercial or medical requirements

The role will ideally be based in Wavre, Belgium, but other European Vaccines Manufacturing locations may be considered with travel to Belgium as required

Key Responsibilities

• Leadership of Product and Technical Life-Cycle Management Teams.
• Oversight of global Validation standards and tools (including both Product and Process Validation).
• Maintain a center of excellence to drive improvement and innovation of key vaccine manufacturing technologies
• Manage all product and technical transfers across global manufacturing operations from product launch onwards.
• Determine and implement global high-level transversal business processes and network optimization relative to Lifecycle Management Products & New Product Introductions.
• Data and business process management.
• Develop improved manufacturing processes applying innovative tools.
• Contribute to the development of new products, ensuring their manufacturing processes are robust, efficient and aligned with operational needs.
• Ensure appropriate support and adherence to the health, safety and environment policies and requirements in the network.
• Ensure compliance of all operations to the relevant Quality and Regulatory requirements.
• Lead change initiatives involving processes, technologies and people, which contribute to the overall effective improvement of GSK Vaccines Supply Chain.
• Build lean sigma expertise across the teams to ensure continuous improvement.
• Share and integrate best practices within the Vaccines Supply Network.
• Lead, train, coach and motivate the management team and employees towards the pursuit of operational excellence and attainment of Good Manufacturing Practices.
• Line manage a significant number of people (~230 FTE) through effective performance management and labor relations excellence.
• Additional matrix leadership of site-based MSAT personnel (~250 associates in local site-based MSAT units who report into the local site leadership).
• Ensure the retention, engagement and development of key talents within the organization.
• Ensure an effective talent management process and succession plans for key roles in the network to minimize operational risks.
• Ensure robust knowledge management process for all Vaccines products & processes.
  

Skills & Experience

Basic qualifications:

• Educated to at least degree level (BSc/MSc or equivalent) in process engineering and/or life sciences in general.
• Deep aseptic manufacturing experience is required, Vaccines experience is a strong plus.
• 15+ years of applicable experience in biopharmaceutical manufacturing / bioprocessing, analytical development and quality-by-design processes.
• Senior management track record with significant team leadership in a complex international organization.
• International/global exposure required.
• Fluency in English.
  

Preferred Qualifications

• PhD or equivalent in life sciences and/or advanced degree in process engineering sciences.
• Proven knowledge of biopharmaceutical processes including understanding of the overall supply chain – both drug substance and drug product.
• Strong technical understanding of how vaccines are manufactured and tested in order to be able to solve technical issues in the processes.
• Insight into vaccine development and analytical processes – able to interface credibly and effectively with R&D and Quality colleagues.
• Operational experience in a at commercial scale biological manufacturing site in addition to technical MSAT expertise.
• Proven Track record in problem solving and global project management.
• Proven ability to plan, manage and lead cross-functional teams and projects to obtain desired business objectives.
• Proven ability to communicate and negotiate effectively with all levels of management across functional, national and cultural boundaries.
• Excellent interpersonal communication and negotiation skills.
• Trans-cultural experience and proven ability to work in a complex and multi-cultural environment.
• Proven Matrix Management skills.
• Excellent skills in project management, change management and team/meeting facilitation.
• Analytical, influencing, negotiation and problem-solving skills.
• Business integration capabilities to translate internal and external best practices.
• Process re-engineering.
• Knowledge of engineering processes (equipment, existing lay outs and guidelines).
• Skilled in conflict resolution and building consensus.
• Understanding of business climate and priorities.
• Ability to translate a manufacturing process into engineering requirements for equipment and facilities.
• Strong regulatory knowledge, with the capability to translate the evolving regulatory environment into adapted manufacturing processes.
• Capability to manage the technical development of a product in alignment with the different development perspectives.
• Capability to influence the architecture of manufacturing processes, facility layouts and approaches to comply with quality constraints.
• French language skills would be advantageous.
  

If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements.

Our goal is to be one of the world’s most innovative, best performing and trusted healthcare companies. We believe that we all bring something unique to GSK and when we combine our knowledge, experiences and styles together, the impact is incredible. Come join our adventure at GSK where you will be inspired to do your best work for our patients and consumers. A place where you can be you, feel good and keep growing.

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