Histology Scientist

작업 내용

Make your mark for patients.We’re here because we want to build the future and transform patients’ lives for the better.At UCB, our people are our experiences and achievements, our passion and drive. That’s why we’re looking for talented individuals with diverse backgrounds and experiences - not just the best and brightest, but those who care about making a meaningful difference in the lives of patients. We promote an environment of diversity, openness, and respect where people can make valuable contributions.An exciting journey lies ahead. Will you join us in pushing the boundaries of what’s possible?To strengthen our Investigative Toxicology team, we are looking for a talented individual to fill the position of: Histology Scientist.The position is based on our site in Braine l’Alleud, Belgium.The investigative toxicology (iTox) team is an integral component of the Non-Clinical Safety Evaluation function of Development Sciences, which as a department provides strategy and support in integrated non-clinical safety, pathology, pharmacokinetics/pharmacodynamics and DMPK, bioanalysis, immunogenicity, and regulatory activities throughout the lifespan of projects, from target identification through to clinical studies.As a Histology Scientist,you will perform the various tasks required for processing and preparing tissue specimens for microscopic examination and analysis by the pathologist. This includes the development and validation of IHC assays or related technics.Scope of the role: you will be focused on supporting toxicology and Tissue Cross-Reactivity studies for therapeutic modalities such as gene therapy, new chemical, and biological entities across all our therapeutic areas (Neurology, Immunology, Bone, and Rare Diseases).You like to work in an environment where you can:

• Be part of an organisation where patients and innovation are fundamental business values, where your expertise matters, and contributions can be felt.
• Be part of a matrix team and opportunity to be involved in different projects, and collaborate with colleagues and project scientists, discuss ideas, and provide constructive challenges and valuable feedback.
• Opportunity to work independently and flexibly in a dynamic laboratory environment to meet project timelines with minimal supervision. In addition, you will receive thorough on-the-job training.

You Will Contribute By

• Carry out all histology processing-related technical steps (sample collection, trimming, paraffin-embedding, decalcification, sectioning, histochemical staining).
• Where appropriate, characterize antibodies, conduct reagent evaluation, and perform reagent qualification/tissue preparation optimization assessments.
• In close collaboration with pathologists, you will develop the pre-clinical IHC assay, troubleshoot technical challenges, and support technical transfer to the Contract Research Organisation (CRO) to ensure validation in the agreed timelines.
• Perform routine data analysis through the various development phases under the pathologist’s supervision.
• Maintain an awareness of new/emerging techniques and tools relevant to the field.

Interested? For this position you’ll need the following education, experience, and skills:

• Candidates should have a BSc or higher academic qualification in a biological discipline.
• Previous experience of working in pharmaceutical drug discovery and development environment with the willingness to learn.
• Solid basis in histology/histopathology and microscopy with proven hands-on direct expertise in pre-clinical or clinical histology, IHC and other related techniques (in situ hybridization)
• Proven track record of validating and optimizing novel fit for purpose IHC/histology-based assays from first principles for pre-clinical safety/tissue cross-reactivity assessments.
• Hands-on direct expertise in slide preparation (tissue processing through to slide cutting and staining).
• Proven collaboration and communication skills with scientists in other disciplines. Good organization skills and attention to detail.
• Adaptable to changing project and organizational priorities and consistently aligned with departmental needs.
• Prior experience with image analysis software, digital imaging, and Artificial Intelligence Software applied to whole slide imaging is a plus.

Why you should applyAt UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration, and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.About Us.UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 7,600 people in all four corners of the globe, inspired by patients and driven by science.At UCB, everything we do start with a simple question: “How will this create value for people living with severe disease?”. We are on a journey to become the patient-preferred biopharma leader by delivering medicines and solutions that improve lives. We want to ensure the creation of patient value, now and into the future, while contributing to a society where a population of 8 billion people and more should be able to live a good life within limited resources of one planet.Curious to know more? Please visit our website www.ucb.com .UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.