Research Scientists / Senior Research Scientist Non-Regulated Bioanalysis

仕事内容

Make your mark for patients.We’re here because we want to build the future and transform patients’ lives for the better.At UCB, our people are our experiences and achievements, our passion and drive. That’s why we’re looking for talented individuals with diverse backgrounds and experiences - not just the best and brightest, but those who care about making a meaningful difference in the lives of patients. We promote an environment of diversity, openness, and respect where people can make valuable contributions.An exciting journey lies ahead. Will you join us in pushing the boundaries of what’s possible?UCB is a leading global pharmaceutical company, dedicated to the research, development, and commercialisation of innovative pharmaceutical and biotechnology products in the areas of Neuroscience, Immunology and Oncology. UCB is a pharmaceutical company with a size that enables it to deliver a significant drug pipeline, whilst remaining agile and innovative.For our talented scientists there is plenty of scope to influence the pipeline and make a difference to patients, and great potential to influence the strategy and drive the science. UCB remains a great opportunity for the individual to get a breadth of experience of the drug discovery pipeline from research through to the clinic, whilst working in a highly collaborative environment to learn, contribute, and gain visibility in a scientific and cross functional setting.To strengthen our Non-Regulatory Bioanalysis Team within the Development Sciences Department, we are looking for a talented Research Scientist / Senior Research Scientist Non-Regulated Bioanalysis, based in Braine-l’Alleud, Belgium.The successful candidate will be an experienced Bioanalytical Scientist with at least 3 years’ experience in a pharma/CRO environment, with a proven track record in small molecule bioanalysis in support of early drug discovery. Experience in large molecule LC-MS bioanalysis and representation in cross-functional project teams would be an advantage.Main Accountabilities

• You will employ your proven bioanalytical expertise to develop and deliver fit-for-purpose LC-MS assays for in vitro and in vivo studies in support of UCB’s pipeline (Novel Chemical Entities and Novel Biological Entities)
• You will troubleshoot these assays by independently resolving technical issues when required
• You will liaise efficiently with internal and external key stakeholders to plan, design, and execute experiments
• You will utilise your scientific judgement to independently interpret analytical data and communicate results in a timely manner
• You will train and mentor other scientists when required
• You will organise and prioritise your workload to meet team and project deliverables
• You will ensure compliance with all health and safety regulations
• This role has great scope to expand, including into functional representation on project teams, where you would provide scientific and technical input to establish a bioanalytical strategy, define deadlines and prioritisation, and provide data interpretation

Interested? For this position you will need the following experience and skills

• At least 3 years’ of relevant quantitative bioanalytical experience, with expert knowledge and understanding of HPLC and LC-MS techniques in the drug discovery DMPK environment (LC-MS/MS and LC-HRMS).
• Excellent working knowledge of analytical software packages (Analyst/SciexOS, XCalibur, Discovery Quant, Compound Discoverer) and automation platforms (e.g. Hamilton platform)
• Demonstrated knowledge in using ELN (Watson, E-Workbook) and Microsoft Office
• In-depth experience with biological sample extraction and preparation techniques.
• A proven track record of providing consistent high-quality bioanalytical support.
• Understanding of assay characterisation and acceptance criteria, such as those required for progression of compounds into development.
• Continual bioanalytical method development and optimisation.
• Trouble shooting of analytical and equipment issues to avoid delays in data generation.
• Interest and track record in supporting in vitro ADME assays, e.g. metabolic stability and protein binding
• Good judgement to assess fit-for-purpose bioanalytical assay performance.
• Experience using a range of analytical techniques in aid of large molecule bioanalysis, such as enzymatic digestion approaches and immunocapture purification would be a plus.
• Demonstrated ability to work effectively in a dynamic laboratory environment to challenging project timelines
• An ability to work in a matrix environment and communicate clearly to colleagues and project scientists, able to discuss ideas, provide constructive challenge and useful feedback
• Adaptable to changing project and organizational priorities and consistently aligned with departmental needs
• English: fluent, both oral and written. French will be considered a plus

We can offer you an informal and open working environment that does not lock scientists into structure and hierarchy. Freedom to take space to pursue your own ideas and make a difference. Opportunity to gain internal and external visibility through interactions with other UCB teams and with world-renown academic investigators. Opportunity to grow both as a drug hunter and leader through participation in project teams and our career/personal development programs.#RANDATUCBAbout Us.UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 7,600 people in all four corners of the globe, inspired by patients and driven by science.At UCB, everything we do start with a simple question: “How will this create value for people living with severe disease?”. We are on a journey to become the patient-preferred biopharma leader by delivering medicines and solutions that improve lives. We want to ensure the creation of patient value, now and into the future, while contributing to a society where a population of 8 billion people and more should be able to live a good life within limited resources of one planet.Curious to know more? Please visit our website www.ucb.com .UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.