Team leader Biology

Research Associate, in vivo work (Leuven, Belgium)

Aelin Therapeutics is a biopharmaceutical company that has secured a 27 M€ investment to pioneer
peptide-based novel modalities to create powerful first-in-class antibiotics and agents against high-value
undruggable human targets. The technology, branded Pept-ins™, harnesses the power of protein
aggregation to induce specific functional knockdown of a target protein and/or cause proteostatic
collapse in cells. The Pept-in™ technology allows for the rational design of novel peptide-based
therapeutics and differentiates itself from other therapeutic modalities through its unique mode of
action, its designability and broad target space. Aelin Therapeutics is seeking to expand its motivated
and innovative team to realize the therapeutic potential of Pept-ins in the field of oncology. The
company is located in Leuven and Ghent, Belgium. The position is vacant for activities in Leuven.
For more information please visit www.aelintx.com.

Role

The role is primarily based in the laboratory, and mainly involves the hands-on animal experimentation
of lead molecules during early drug discovery. The candidate should work effectively in a fast-paced,
dynamic, and exciting start-up environment.

The ideal candidate will have a Bachelor or Master degree in life sciences (biotechnology, biomedical,
biochemistry), with practical experience in handling of animals and oncology models in rodents.
Experience in working as a researcher in biotechnology and/or drug discovery in the biopharmaceutical
industry is desirable. Additional skills in biochemistry and biotechnology will be of benefit. The candidate
will work with R&D scientists to support the R&D strategy.

Responsibilities
Growth of tumor cells in vitro for inoculation in mice
Inoculation of tumor cells
Measuring of tumor growth, mouse weight and recording data
Drug administration by intravenous (mandatory), intraperitoneal, subcutaneous, or oral

routes, and blood sampling from different body sites, and preparation of plasma or serum
samples

Assessment of wellbeing of mice during experiments
Sampling and processing of organs
Presenting work summaries, documenting work for archival

Key skills
Qualified as technical assistant or equivalent
Educated in animal in vivo experimentation (FELASA-B)
Minimum of 1-2 years of experience in in vivo experimental work with rodents
Experience with oncology models in rodents
Experience with the most common drug administration (including intravenous), blood

sampling methods, organ collection and processing
Experience and proficiency in aseptical working
Familiar with MS-Office and GraphPad Prism programs, plus with familiarity of programs

related to animal experimentation and documentation
Flexible with ability to quickly become acquainted with new tasks

AelinTx.com

Excellent written and oral skills (including English)
Motivated team player with open communication and independent working style
Reliable and well-organized with a pro-active attitude
Eye for detail and accuracy with an extensive troubleshooting and problem-solving skills
Additional in vitro techniques are considered as advantageous

Our offer
A competitive salary and benefits package
An entrepreneurial and stimulating working environment in an ambitious start-up biotech company
Excellent career development opportunity, with exposure to all aspects of R&D in the company

Do you have the right qualifications, a bright mind, sharp instincts, collaborative spirit, and innovative
vision and are you interested in joining our entrepreneurial team? Then forward a short motivation
letter and your CV to careers@aelintx.com