Senior/Principal Scientist Medicinal Chemistry

☞ Augustine Therapeutics

Vue: 140

Jour de mise à jour: 16-11-2025

Localisation: Leuven Flemish Brabant

Catégorie: Autre

Industrie:

Type d’emploi: Full-time

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le contenu du travail

Company Description

Augustine Therapeutics is a pharmaceutical company focused on discovering and developing innovative HDAC6 inhibitor medicines for patients with Charcot-Marie-Tooth disease (CMT), peripheral neuropathies, neurodegenerative disorders & cardio-metabolic diseases. The company is based in Leuven and is supported by Asabys Partners, Eli Lilly and Company, V-Bio Ventures, PMV, AdBio Partners, VIB, Gemma Frisius Fund, and CMT Research Foundation. Augustine Therapeutics is rooted in ground-breaking research at VIB and KU Leuven.

Responsibilities

The Senior/Principal Scientist will play a critical role in our drug discovery and development efforts, leveraging their expertise in both synthetic and medicinal chemistry. With a PhD and 5-10 years of experience in small molecule drug discovery, the ideal candidate will run projects within the Augustine Therapeutics pipeline. Familiarity with CNS drug design, structure-based drug design, PET tracer development, patent drafting, grant application writing and working with external parties is a plus. The therapeutic area of expertise will be in the neuroscience, cardiology, or metabolic disease space. The candidate must demonstrate a proven track record of leadership within a medicinal chemistry team, the ability to learn fast and adapt in a dynamic semi-virtual environment, a hands-on and can-do attitude.

Qualifications

• PhD in (Medicinal) Chemistry or Pharmacy.

• 5-10 years of experience in drug discovery.

• Knowledge of state-of-the art synthetic organic chemistry and outstanding synthetic troubleshooting skills.

• Experience with interpreting both in vitro and in vivo pharmacology studies.

• Proven track record of research and expertise in medicinal chemistry, preferably in a relevant therapeutic area (neuroscience, cardiology, or metabolic diseases).

• Excellent project management and leadership skills.

• Strong analytical, problem-solving, and data interpretation abilities.

• Effective communication and scientific writing skills.

• Experience with predictive models and AI tools is a plus.

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Date limite: 31-12-2025

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