N> Biomarker Lead

工作内容

Make your mark for patients.

We’re here because we want to build the future and transform patients’ lives for the better.

At UCB, our people are our experiences and achievements, our passion and drive. That’s why we’re looking for talented individuals with diverse backgrounds and experiences - not just the best and brightest, but those who care about making a meaningful difference in the lives of patients. We promote an environment of diversity, openness, and respect where people can make valuable contributions.

An exciting journey lies ahead. Will you join us in pushing the boundaries of what’s possible?

To strengthen our Precision Medicine and Biomarker team, we are looking for a high caliber, self-motivated,Precision Medicine and Biomarker Leadto be based in Braine l’Alleud, Belgium.

The Precision Medicine and Biomarker Lead is accountable for devising the clinical biomarker strategy for assigned projects across their development lifecycle ie starting from the pre-clinical phase to clinical proof of concept, and potentially through to late development/market. This will include identifying and proposing innovative and feasible biomarkers aligned to the clinical development strategy to build the data package and support clear and efficient decision making, optimal targeting of the drug to specific patient populations and enhancing overall probability of successful drug development and approval. The TM Biomarker Lead will be considered a UCB Subject Matter Expert in biomarkers, their development and implementation. The role will therefore require deep understanding and appreciation of the scientific, technical, regulatory, intellectual property and preferably commercial considerations for successful biomarker implementation to drug development programmes. The TM Biomarker Lead will be required to work closely with all members of the Project team and Clinical team responsible for delivering the clinical development strategy. The role will include leadership of the Biomarker Subteam (a multidisiplinary transversal team) which is responsible for delivery of the biomarker strategy to time and budget. The encumbent thereby is required to have not only strong technical and strategic abilities, but also excellent interpersonal and negotiation skills.

Major Accountabilities

• Lead the project biomarker subteam to deliver appropriate planning and operationalization for translational and clinical biomarker strategies as and when required
• Work to support the development and adoption of biomarker led drug development strategies in UCB Project teams to add value to drug projects.
• Ensure that biomarker assays and diagnostic tests are delivered to rigorous scientific and technical standards, whilst being synchronised with the timing of clinical trials and meeting regulatory standards to demonstrate analytical validation and clinical utility
• Work with UCB regulatory experts to assist in regulatory responses in respect of biomarker development
• Work with internal and external scientific experts to review biomarker practice and establish a scientific and technical knowledge base of available biomarker assays and appropriate assay platforms together with appropriate organisational partners for their delivery
• Agree strategic objectives, high-level project plan and milestones with UCB project teams
• Be accountable for the delivery of agreed plans to time, budget and quality and provide updates on the progress, risks and opportunities of the agreed plans to the appropriate governance bodies for review
• Identify, manage and mitigate risk to delivery
  

Interested? For this position you’ll need the followingeducation,experienceandskills:

• PhD or equivalent with 8 or more years of related experience post-degree
• Strong understanding of the implementation and use biomarkers in an industrial drug development environment. Spanning early discovery to late-stage patient stratification.
• Good knowledge of (early) clinical development with proven track record of successful contribution to projects.
• Neuroscience background/ PhD in Neuroscience, with deep understanding of Neuroscience, especially Neurodegeneration or Epilepsy or Neuroinflammation
• Knowledge of overall drug development process.
• Ability to present a well-reasoned business case, and influence others to support cross functional implementation of new initiatives and projects.
• Ability to communicate effectively with internal and external opinion leaders including pharmaceutical regulatory agencies, e.g. FDA, EMEA.
• Ability to work in a matrix type environment.
• High performer with strong team-commitment. Must be a strong team player with abilities to work in a multicultural environment. Empowers and coaches teams to interpret and synthesize information that leads to insights.
• Is innovative, can manage uncertainty.
• Ability to work independently and to solve complex problems and multiple projects in supervisory capacity.
  

Why you should apply

We can offer you an informal and open working environment that does not lock scientists into structure and hierarchy. Freedom to take space to pursue your own ideas and make a difference. Opportunity to gain internal and external visibility through interactions with other UCB teams and with world-renown academic investigators. Opportunity to grow both as a drug hunter and leader through participation in project teams and our career/personal development programs.

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.

If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.

About Us.

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 7,600 people in all four corners of the globe, inspired by patients and driven by science.

At UCB, everything we do start with a simple question: “How will this create value for people living with severe disease?”. We are on a journey to become the patient-preferred biopharma leader by delivering medicines and solutions that improve lives. We want to ensure the creation of patient value, now and into the future, while contributing to a society where a population of 8 billion people and more should be able to live a good life within limited resources of one planet.

Curious to know more? Please visit our website www.ucb.com .

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.